CD3 anticorps

N° du produit ABIN2567515

Cet anticorps anti-CD3 est un anticorps Souris Monoclonal détectant CD3 dans FACS, IP, IHC, Func, IF et WB. Adapté pour Humain.

Aperçu rapide pour CD3 anticorps (ABIN2567515)

Antigène: CD3

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Functional Studies (Func), Immunofluorescence (IF), Western Blotting (WB)

Clone: UCHT1

Détail du produit anti-CD3 anticorps

Specificité: The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex.

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Stock: 4 °C

Stockage commentaire: The product should be stored undiluted at 4°C. Do not freeze.

Détails sur CD3

Antigène: CD3

Autre désignation: CD3

Sujet: The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3ε. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.

ID gène: 916

UniProt: P07766

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway